Syllabus Information

1.4. Activities and key dates

For students enrolled in the subject, places, times and dates of lectures and practical sessions will be public via Bulletin Board advertisements of the grade on the platform Moodle at the University of Zaragoza, https://moodle2.unizar.es/add/, and in the moodle page for the course. These routes will be also used to communicate enrolled students their distribution by groups of practical sessions, which will be organized by the coordination of degree.  Provisional dates will be available on the website of the Faculty of Sciences in the corresponding section of the Degree in Biotechnology: https://ciencias.unizar.es/grado-en-biotecnologia.

In this web there will be also available the dates of exams.

5.1. Methodological overview

The methodology followed in this course is oriented towards achievement of the learning objectives . It favors the acquisition of knowledge related to Pharmacology. A wide range of teaching and learning tasks are impolemented, such as theory sesions, practice sessions, assignments, and tutorials.

The  subject has a basic orientation. The proposed activities are directed to understand and assume the fundamental principles of the Pharmacology. Moreover, the acquisition of conceptual, manual and technique knowledge will help to the students to manage the process of the drugs biotransformation from the point of  view both, of molecular and cellular mechanisms, which are essential to the future of  the  Biotechnology professionals.

The acquired knowledge from the theory sessions will be complemented with the practice sessions where the student will learn about the different methods usually used in Pharmacology and its practical application.

Tutorials will be held to follow the learning process of the students. They can choose between the conventional tutorials and specific tutorials related with the practical-classes as seminars.

Students are expected to participate actively in the class throughout the semester.

Classroom materials will be available via Moodle. These include a repository of the lecture notes used in class, the course syllabus, as well as other course-specific learning materials.

Further information regarding the course will be provided on the first day of class.

5.2. Learning tasks

The course includes 6 ECTS organized according to:

- Theory sessions (1,28 ECTS): 32 onsite hours

- Pratice sessions (0,72 ECTS): 18 onsite hours

- Tutorial sessions (0,28 ECTS): 7 hours onsite hours

- Autonomous work (3,64 ECTS) : 91 hours

Theory sessions: 32 face to face participative sessions lasting 50 minutes each one. The professor will present theorical contents which will be available at the Moodel website.

In the lectures a presentation and explanation of the subject contents will be held in order to prepare the students for achieving the  competences and leartning outcomes as required.

Practice sessions: the practice sessions will take play during two weeks and will be divided into two moduls. Students are divided into smaller groups.

5.3. Syllabus

Theory sessions

Section 1. General Principles of Pharmacology

          Topic 1. Pharmacology concepts: Active pharmaceutical ingredient, drug.  Drug life cycle research.

          Topic 2. Pharmacokinetics: Drug passage across the membrane. Routes of administration. Drug absorption. Drug distribution. Drug metabolism and excretion.

          Topic 3. Pharmacodinamics: Mechanism of drug actions. Pharmacological actions. Drug receptor concept and types. Dose-response curves. Pharmacological interactions.

          Topic 4. Side effects

      Topic 5. Pharmacogenetics and Pharmacogenomics

      Topic 6. Omic Sciences

      Topic 7. Food-drug interactions. Nutrigenomics

      Topic 8. Toxicology: Intoxication with drugs

      Topic 9. Drug development

      Topic 10. Clinical Trials and Pharmacoepidemiologa

      Topic 11. Socioeconomic aspects of the drugs

Section 2. Pharmacology of Systems

      Topic 1. Pharmacology of Autonomic Nervous System

      Topic 2. Pharmacology of Central Nervous System

      Topic 3. Pharmacology and the Immune System

      Topic 4. Chemotherapeutic Agents

      Topic 5. Pharmacology of  Blood Disorders

      Topic 6. Pharmacology of Endocrine System: Thyroide hormones. Antidiabetic drugs. Cortical steroids. Lipid-lowering drugs. Pharmacology of the calcium and phosphorus. Sex hormones

      Topic 7. Drugs of abuse

      Topic 8. Pharmacology of doping

Practice sessions of Pharmacology

1^st Module

• Simulation on drug administration at Cardiovascular level
• Workshop: Routes of drug administration and pharmaceutical forms

2^nd  Module

• Practical on-site activities: visiting  to  pharmaceutical company
• Pharmacology Congress on University Teaching

5.4. Course planning and calendar

Schedules of lectures and practice will coincide with the officially established and will be available at: https://ciencias.unizar.es/grado-en-biotecnologia.

The places, calendar and groups for training and practical sessions will be established in coordination with the rest of maters at beginning of course. The Coordinator will produce the groups of students for these activities at beginning of course to avoid overlaps with other subjects

5.5. Bibliography and recommended resources

• Las bases farmacológicas de la terapéutica / [editor, Laurence L. Brunton ; editores asociados, John S. Lazo, Keith L. Parker] ; traducción, José Rafael Blengio Pinto, Jorge Orizaga Samperio, Ana María Pérez-Tamayo Ruiz . 11ª ed. México D.F. [etc.] : McGraw-Hill Interamericana, cop. 2007
• Lorenzo Velázquez, Benigno. Farmacología básica y clínica / Velázquez ; [colaboradores], P. Lorenzo ... [et al.]. 18ª ed. Madrid [etc.] : Editorial Médica Panamericana, 2008
• Farmacología / H.P. Rang ... [et al.] . 6ª ed. Madrid [etc.] : Elsevier, D.L. 2008
• Farmacología fundamental / autores, Alfonso Velasco Martín ... [et al.] . 1ª ed. en español, [reimp.] Madrid [etc.]: McGraw-Hill Interamericana, D.L. 2004
• Farmacología humana / director, Jesús Flórez ; directores asociados, Juan Antonio Armijo, África Mediavilla . 5ª ed. Barcelona [etc.] : Masson, 2008
• Integrated pharmacology / Clive Page ... [et al.] . 2nd.ed. Edinburgh [etc.]: Mosby, 2004